论文题名(中文): | RNF13泛素化调控内体TLR信号通路与ADAR1介导的RNA编辑异常在自身免疫性疾病中的机制研究 |
姓名: | |
论文语种: | chi |
学位: | 博士 |
学位类型: | 学术学位 |
学校: | 北京协和医学院 |
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专业: | |
指导教师姓名: | |
论文完成日期: | 2025-04-01 |
论文题名(外文): | Mechanistic Study of RNF13 Ubiquitination-Regulated Endosomal TLR Signaling Pathway and ADAR1-Mediated Abnormal RNA Editing in Autoimmune Diseases |
关键词(中文): | |
关键词(外文): | rheumatoid arthritis anti-MDA5 antibody-positive dermatomyositis Toll-like receptor type I interferon RNA editing |
论文文摘(中文): |
天然免疫系统作为机体抵抗病原体入侵的第一道防线,其识别和调控机制一直是免疫学领域的研究热点。 |
论文文摘(外文): |
The innate immune system, serving the first defense line of the human body against pathogen invasion, its recognition and regulatory mechanisms have long been the subject of intensive investigation in immunology. |
开放日期: | 2025-05-23 |